2. Signaling Pathways
  3. Vitamin D Related/Nuclear Receptor
  4. Progesterone Receptor
  5. Progesterone Receptor Agonist

Progesterone Receptor Agonist

Progesterone Receptor Agonists (63):

Cat. No. Product Name Effect Purity
  • HY-N0437
    Progesterone
    		Agonist 99.79%
    Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
  • HY-B0469
    Medroxyprogesterone acetate
    		Agonist 99.88%
    Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors.
  • HY-B0648
    Medroxyprogesterone
    		Agonist 99.30%
    Medroxyprogesterone (17α-Hydroxy-6α-methylprogesterone) is a synthetic human variant of progesterone that is a progesterone receptor agonist with oral activity. Medroxyprogesterone can induce cell proliferation through the PI3K/Akt signaling pathway. Medroxyprogesterone has an inhibitory effect on atherosclerosis in mice. The progesterone agonist activity of Medroxyprogesterone is less effective than Medroxyprogesterone acetate (HY-B0469).
  • HY-B0084S4
    Dienogest-13C,15N,d4
    		Agonist
    Dienogest-13C,15N,d4 (STS 557-13C,15N,d4) is the 13C, 15N and deuterium labeled isotope of Dienogest (HY-B0084). Dienogest (STS-557) is an orally active and selective progesterone receptor agonist that effectively reduces the gene expression of COX-2, mPGES-1 and aromatase. Dienogest also inhibits the mRNA and protein expression of PGE2 synthase and the activation of NF-κB. Dienogest can be used in studies of endometriosis, menopause and menorrhagia.
  • HY-B0891
    17α-Hydroxyprogesterone
    		Agonist 99.96%
    17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progesterone that serves as a chemical intermediate in the biosynthesis of other steroid hormones, including glucocorticoids, androgens, and estrogens.
  • HY-B0084
    Dienogest
    		Agonist 99.90%
    Dienogest (STS-557) is an orally active and selective progesterone receptor agonist that effectively reduces the gene expression of COX-2, mPGES-1 and aromatase. Dienogest also inhibits the mRNA and protein expression of PGE2 synthase and the activation of NF-κB. Dienogest can be used in studies of endometriosis, menopause and menorrhagia.
  • HY-B0111
    Drospirenone
    		Agonist 98.45%
    Drospirenone (Dihydrospirorenone) is an orally active fourth-generation progestin that interacts with the progesterone receptor (PR) and androgen receptor (AR). Drospirenone significantly decreases both plasminogen activator inhibitor-1 (PAI-1) and tissue plasminogen activator (tPA) via the AR. Drospirenone can produce DNA damage in bone marrow cells of female mice. .
  • HY-B0257A
    Dydrogesterone
    		Agonist 99.88%
    Dydrogesterone is a potent, orally active progestogen indicated in a wide variety of gynaecological conditions related to progesterone deficiency.
  • HY-B0554
    Norethindrone
    		Agonist 99.37%
    Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea.
  • HY-N0437R
    Progesterone (Standard)
    		Agonist 99.53%
    Progesterone (Standard) is the analytical standard of Progesterone. This product is intended for research and analytical applications. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
  • HY-119384
    Promegestone
    		Agonist ≥98.0%
    Promegestone (R-5020), a progestin, is a potent progesterone receptor (PR) agonist. Promegestone has the potential for endocrine regulation and cancer research.
  • HY-12516
    Desogestrel
    		Agonist 99.65%
    Desogestrel (Org-2969) is a third-generation progesterone analogue contained in many oral contraceptive preparations. Desogestrel is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • HY-B0521
    Altrenogest
    		Agonist 99.97%
    Altrenogest (Allyltrenbolone) is a progestogen structurally related to veterinary steroid trenbolone.
  • HY-15606
    Tanaproget
    		Agonist 99.87%
    Tanaproget (NSP-989) is a novel non-steroidal progesterone receptor agonist.
  • HY-B0110
    Gestodene
    		Agonist 99.90%
    Gestodene is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • HY-13071
    Nestoron
    		Agonist 99.83%
    Nestoron (ST-1435) is a 19-norprogesterone derivative with high affinity and selectivity for progesterone receptors. Nestoron is a highly selective and potent progestogen that can be used as a hormonal contraceptive.
  • HY-B1095
    Chlormadinone acetate
    		Agonist ≥98.0%
    Chlormadinone acetate is a steroidal progestin, with antiandrogen and antiestrogenic effects.
  • HY-B0648R
    Medroxyprogesterone (Standard)
    		Agonist 99.29%
    Medroxyprogesterone (Standard) is the analytical standard of Medroxyprogesterone. This product is intended for research and analytical applications.
  • HY-105634A
    Nomegestrol acetate
    		Agonist 99.94%
    Nomegestrol acetate is an orally active, highly selective progestogen and a progesterone receptor complete agonist. Nomegestrol acetate inhibits ovulation. Nomegestrol acetate is also effective in inhibiting the proliferation of human endometrial cancer RL95-2 cells in vitro and in vivo. Nomegestrol acetate can be used in cancer (especially endometrial cancer) and contraceptive studies.
  • HY-B0891S
    17α-Hydroxyprogesterone-d8
    		Agonist 99.51%
    17α-Hydroxyprogesterone-d8 is the deuterium labeled 17α-Hydroxyprogesterone. 17α-Hydroxyprogesterone (17-Hydroxyprogesterone) is an endogenous progestogen as well as chemical intermediate in the biosynthesis of other steroid hormones, including the corticosteroids and the androgens and the estrogens.